Treatment significantly reduces chemotherapy-induced hearing loss in children

(Children's Hospital Los Angeles) Investigators from Children's Hospital Los Angeles and 37 other Children's Oncology Group hospitals in the US and Canada have determined that sodium thiosulfate prevents cisplatin-induced hearing loss in children and adolescents with cancer. Results of this randomized, controlled, phase 3 study, called ACCL0431, have been published in the early online edition of Lancet Oncology.